The Mummy's Ghost is a 1944 American horror film directed by Reginald Le Borg. It is the second of three sequels to that company's The Mummy's Hand of 1940. The film is the sequel to The Mummy's Tomb (1942). Lon Chaney, Jr. again takes on the role of Kharis the mummy. The story was continued in the 1944 sequel The Mummy's Curse.
Andoheb, the aging High Priest of Arkam, has summoned Yousef Bey to the Temple of Arkam to pass on the duties of High Priest. Meanwhile, in Mapleton, Massachusetts, Professor Matthew Norman, who had examined one of Kharis' missing bandage pieces during the mummy's last spree through Mapleton, also explains the legends of the Priests of Arkam and Kharis to his history class, who are less than believing. After the lecture ends, one of the students, Tom Hervey, meets up with his girlfriend Amina Mansori, a beautiful woman of Egyptian descent. However, a strange, clouded feeling in her mind occurs whenever the subject of Egypt is mentioned.
Back in Egypt, Andoheb informs Yousef Bey that Kharis still lives and that Yousef's mission is to retrieve Kharis and the body of Ananka and return them to their rightful resting place in Egypt. Yousef Bey pledges his devotion before Andoheb explains that during each full moon, Yousef Bey is to brew the fluid from nine tana leaves. Kharis will sense this and find the leaves wherever they are. On performing the ceremony, Kharis heads toward them but passes the home of Amina who follows Kharis in a trance-like state. Kharis arrives at the home of Professor Norman, strangles him, and drinks the fluid of the tana leaves. Amina sees Kharis, which snaps her out of her trance and causes her to faint and forms a strange new birthmark on her wrist.
The next morning, the Sheriff and Coroner discover a strange mold around the dead professor's throat – a sign they both know to mean that the mummy stalks Mapleton again. Later, Yousef Bey, who has arrived in Mapleton, calls on Amon-Ra to aid him in his quest and begins to brew the tana leaves to summon Kharis. Kharis heads towards him, killing a farmer along the way. The sheriff soon arrives on the scene and organizes a search party.
The next day, at the Scripps Museum, Yousef Bey emerges after hours from a hiding place as Kharis breaks into the museum. Kharis attempts to touch the mummified body of Anaka, but it disintegrates. Yousef Bey realizes that Ananka's soul has been reincarnated into another form as Kharis begins destroying the exhibit, killing the museum security guard. Police Inspector Walgreen and Dr. Ayad arrive later and decide to use the tana leaves to attract and trap Kharis in a pit.
Meanwhile, Amina disregards the Sheriff's warning and decides to elope with Tom to New York. The two make plans to leave early the next morning. Yousef Bey calls upon Amon-Ra to lead him to the new home of Ananka's soul and then sends Kharis in that direction to find Ananka.
As Inspector Walgreen sets the trap by for Kharis, Kharis immediately heads toward the Norman home. Amina is awakened by his approach and hypnotically wanders into the yard where Kharis recognizes her as the carrier of Ananka's soul. Amina faints as Kharis carries her away. Amina's guardian Mrs. Blake phones Tom and tells her story to Inspector Walgreen, Sheriff Elwood, and a large group of volunteers. Kharis arrives at the mill and presents Amina to Bey. Bey recognizes the birthmark as the symbol of the priests of Arkam. Amina awakens and the priest informs her that she is the reincarnation of Ananka.
Yousef Bey falls for Amina's beauty and desires to keep her alive as his bride with the tana leaves. This plan enrages Kharis, leading to a fight where Bey falls out a window to his death. Tom enters and after failing to stop Kharis, finds him leaving with Amina. A mob pursues Kharis into a swamp where both him and the rapidly aging Amina sink.