The Amazing Colossal Man, released October 25, 1957, was directed by Bert I. Gordon and starred Glenn Langan. As was popular with many films in the 1950s, the central antagonist, Lt. Col. Glenn Manning, was created by means of nuclear radiation that caused him to grow and lose his humanity.
Glenn Langan plays Lt. Col. Glenn Manning, an officer in the U.S. Army who suffers serious burns to over 90% of his body following an inadvertent exposure to plutonium radiation from a bomb blast. He miraculously survives the explosion and his burns completely heal, but the radiation causes him to abnormally grow into a 60-foot-tall giant. At this size, his heart is unable to supply sufficient blood to his brain and he gradually goes insane.