Sergei Vladimir is a high-ranking Russian employee of Umbrella and the main antagonist of Resident Evil: The Umbrella Chronicles.
Following the fall of the Soviet Union, he approached the Umbrella Corporation and quickly became one of the company's top officers. He became personally acquainted with Umbrella's founder, Ozwell E. Spencer, who began to rely on Sergei as a loyal and effective enforcer. Sergei subsequently formed and led Umbrella's UBCS, as well as Umbrella's internal espionage organization, Monitor.
Agents that answered directly to Sergei included the likes of Nicholai Ginovaef. Sergei undertakes the Umbrella Corporation's most important tasks through the Resident Evil series, including stealing the Red Queen from the Arklay Research Facility, extracting an Umbrella executive from Raccoon City before its destruction, and securing important research information. Sergei is killed by Albert Wesker while attempting to prevent him from stealing a database containing the Umbrella Corporations most important documents and research data.