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Resident Evil: Extinction is a 2007 action horror film directed by Russell Mulcahy and written by Paul W. S. Anderson. A direct sequel to Resident Evil: Apocalypse (2004), it is the third installment in the Resident Evil film series, which is loosely based on the Capcom survival horror video game series of the same name. The film follows the heroine Alice, along with a group of survivors from Raccoon City, as they attempt to travel across the Mojave desert wilderness to Alaska and escape a zombie apocalypse.

In November 2005, Screen Gems gained the rights for the third installment in the franchise, which was then subtitled Extinction. Anderson returned as a writer, and filming took place in Mexico with Mulcahy as the director.

Resident Evil: Extinction was released in the United States on September 21, 2007 and was released in the United Kingdom on October 12, 2007, by Sony Pictures Releasing. The DVD and Blu-ray versions were released in North America on January 1, 2008. The film grossed $147 million against a $45 million budget. A fourth film, Resident Evil: Afterlife, was released in 2010.


A cloned Alice wakes up in a mansion, wanders through its halls, and is forced to escape several security traps, mirroring some events of the first film. During her escape, Alice makes use of new telekinetic powers, killing a security guard. However, she is eventually killed by a bouncing mine hidden in the floor. Her body is dumped into a pit filled with dozens of other Alice clones, representing the failed results of the Umbrella Corporation's ongoing Project Alice.

Following Umbrella's attempts to cover up the contamination of Raccoon City, the T-Virus spreads around the world, devastating not only the human population, but the entire global environment in the next five years. The real Alice wanders the wasteland that was once the Southwestern U.S., and after fighting off a family of marauders, discovers information in an abandoned notebook referring to an uninfected area in Alaska. Alice realizes that she, like her clones, has developed telekinesis.

Meanwhile, Dr. Alexander Isaacs, the former head of Project Alice and top official at the North American Umbrella facility in Nevada, considers Alice's recapture a top priority due to her ability to bond with the T-virus without mutating. At a meeting of Umbrella executives, Isaacs attempts to persuade Umbrella's board of directors that he can use Alice's blood to develop a treatment that will tame the infected zombies. Isaacs' plan is dismissed by Umbrella CEO Albert Wesker, who orders Isaacs to return to his work with the clones.

Simultaneously, a convoy of survivors led by Claire Redfield and Raccoon City survivors Carlos Oliveira and L. J. Wade travels across the country in search of supplies and safe harbor. While searching a motel, L. J. is bitten by a zombie. Fearing the harsh fate that awaits him, he chooses not to tell the other survivors about the injury. The next morning, the convoy is attacked by a murderous flock of infected crows. With the team nearly overwhelmed, Alice appears and defeats the remaining crows with her newfound telekinesis, though falling unconscious. Awaking shortly thereafter, Alice is introduced to Claire and tells her about the notebook, convincing her to take the convoy to Alaska.

Isaacs' attempts to domesticate the infected lead to the creation of a new zombie breed. Wesker's security officer, Captain Alexander Slater, reports on Isaacs' disregard for Umbrella regulations. Wesker tasks Slater with watching Isaacs, telling him to kill the scientist if he disobeys orders again. Tracing an energy pattern sent out by Alice's telekinesis, Umbrella triangulates her location. Desperate to reclaim Alice for the sake of achieving his goals, Dr. Isaacs sends his new zombies to ambush the convoy against Wesker's specific orders. During the attack, most of the convoy is killed, and L.J. succumbs to his infection, biting Carlos. Umbrella tries to shut Alice down remotely, but she breaks free from Umbrella's programming and continues to fight. She finds Isaacs at the scene, and he is bitten as he flees via helicopter. Alice and K-Mart use Isaacs' computer to track the helicopter's flight path, leading them to Umbrella's underground facility.

The convoy approaches Umbrella's facility, which is surrounded by thousands of zombies. Carlos sacrifices himself by plowing his truck into the zombie mob, blowing the rig apart and giving both Alice and Claire time to load survivors into the helicopter. Following the rescue, Alice decides to stay behind. Under Wesker's orders, Slater and a group of Umbrella commandos take control of Isaacs' lab, where he's injected himself with massive doses of anti-virus in an attempt to counteract his infection. Slater shoots him, triggering a mutation that transforms Isaacs into the monstrous Tyrant. Though he retains his intelligence, Isaacs kills Slater along with everyone else in the facility, ultimately finding himself trapped in the lab's lower levels.

Approaching the scene, Alice meets a holograph of the Red Queen's "sister" AI, the White Queen. She informs Alice that her blood can cure the T-virus, defends the Red Queen's prior actions, and reveals what happened to Dr. Isaacs. On her way to the lab's lower levels, Alice encounters one of her clones, which awakens but appears to die from shock soon after. Alice discovers Isaacs/Tyrant, defeating him after leading him to the replica of The Hive's laser corridor featured in the film's opening. Just as Alice is about to meet the same fate, the system is deactivated by the clone, who is still alive.

Later in Tokyo, Wesker informs his fellow Umbrella executives that the North American facility has been lost. Alice appears during the meeting, declaring that she and her "friends" (the other clones) are coming for him.