Ramon Salazar (voiced by Rene Mujica) is a secondary antagonist in Resident Evil 4.
Salazar is the castellan of the castle affiliated with Los Iluminados. He comes from a noble family, who were responsible for sealing Las Plagas beneath the castle's grounds. Years later, Osmund Saddler, a cultist who worships Las Plagas, persuaded Salazar to unearth the parasites, causing them to spread across the local area.
Salazar controls the Ganados and orders them to kill Leon Kennedy and apprehend Ashley Graham. He merges with his second Verdugo in a Queen Plaga to become a gigantic abomination in a desperate attempt to defeat Kennedy, but perishes during the ensuing fight.