Rain Ocampo, played by Michelle Rodriguez, is introduced in the first Resident Evil film, in which she works for the Umbrella Corporation's commando force.
During the outbreak in The Hive, Rain and the other operatives are sent down to shut the Red Queen down and contain the infection. During The Hive incident, Rain and Alice become very close. Rain is bitten by one of the infected and is on the point of death when Alice administers the antivirus to her. However it is too late to reverse the effects so that Rain dies and has to be killed by Matt Addison when she revives as a zombie.
Several clones of Rain Ocampo are introduced in Resident Evil: Retribution, including a "Good Rain", created as a test subject for the Umbrella Corporation's live tests on the human response to viral outbreaks, a "Bad Rain", who works for Jill Valentine, and a "Zombie Rain". Good Rain, along with a little girl named Becky who is the daughter of an Alice clone, survives a test scenario of the T-Virus in a suburban situation. Good Rain is killed when a Licker throws her into a pillar, breaking her neck. Bad Rain helps fight against Alice and her allies and injects herself with the Las Plagas parasite, making her super-strong and invincible. Bad Rain kills Luther West and nearly kills Alice before Alice shoots out the ice under her feet, dropping her into an ocean full of Las Plagas zombies who devour her. During a deleted scene, Zombie Rain is seen during the New York simulation. She charged Ada Wong and Alice from the left, emerging from an alley and attempted to blindside Alice. Alice reacts quickly enough that she kills the clone with a shot to the head.