Meredith Vickers, played by Charlize Theron, is a character in the film Prometheus.
Vickers, an upper-level employee of the Weyland Corporation, is Peter Weyland's estranged daughter and joins the Prometheus expedition as a corporate overseer. After the ship settles down in 2093, she explains her lack of faith in the mission to Elizabeth Shaw and Charlie Holloway. While monitoring spectagraphs (sensors deployed by Fifield), Vickers is seduced by Janek in her quarters.
She collaborates with David 8, who gives her a feed of his mission to explore the secrets of the Juggernaut, but is denied access since he is directed by Peter Weyland. When Holloway becomes infected Vickers bars him from the ship and, at his insistence, incinerates him with a flamethrower.
As Weyland prepares to meet the Engineer, she warns him that "a king has his reign, and then he dies". After seeing her father's death on a live feed, Vickers orders the Prometheus to return to Earth but Shaw convinces Janek to ram the Prometheus into the embarking Engineer ship. Realizing that she cannot escape, Vickers and her life-support unit are jettisoned to LV-223's surface. Shortly after landing she is caught in the path of the rolling Engineer ship, which crushes her.