Lindsey Wallace first appears in 1978's Halloween as she is babysat by Annie Brackett, where she sits and watches The Thing from Another World. After Annie leaves the Wallace house to go and pick up her boyfriend, Paul, she leaves Lindsey in the care of Laurie Strode, who is babysitting Tommy Doyle at his house. Before leaving to pick up her boyfriend, Annie is killed by Michael Myers. Lindsey is then seen asleep with Tommy while Laurie goes to check on Annie, Paul, Lynda Van Der Klok and Bob Simms. Lindsey and Tommy later open the door for Laurie as she is chased back into the house by Michael. After locking themselves in the bathroom and Laurie being attacked twice, Laurie tells them to go to the Mackenzies' house. She appears in Halloween II in a recap of the first film's final moments. She also appears in Rob Zombie's remake in a role much like the one she has in the original. She is played by Kyle Richards in the first and second films and Jenny Gregg Stewart in the 2007 remake.
A character by the name of Lindsey appears in the fourth movie in a cameo played by Leslie L. Rohland, but it is uncertain if this is in fact Lindsey Wallace from the original movie or a separate character.
In the official sequel comic, Halloween: One Good Scare, set in 2003, Lindsey is 32 years old and in the care of David Loomis at Smith's Grove. Unable to escape Michael, she is taken from the hospital by him and later found dead with more than thirteen knives stabbed into her.