Helena Harper is a character in the video game Resident Evil 6.
Helena is an agent in the Secret Security Service (USSS) and the personal bodyguard of U.S. President Adam Benford. Harper is a former CIA operative, who receives a second-chance with the USSS after facing two suspensions for using excessive force to defend her family. Derek C. Simmons blackmails Harper into helping his organization cause a C-Virus outbreak in Tall Oaks by kidnapping Helena's sister, Deborah. Benford is infected in the ensuing viral outbreak and becomes a zombie, prompting Leon Kennedy to reluctantly shoot him in the head.
Harper and Kennedy work together to locate Deborah before learning Simmons has mutated her into a BOW. Helena is forced to kill her sister, and reveals she worked with Simmons to cause the C-virus outbreak under duress. She eventually confronts and kills Simmons in Lanshiang, China. Harper is cleared of any wrongdoing after the government investigates Simmons’ background.