Gwen Campbell, portrayed by Jessica Heafey, is a character in the television Supernatural.
Gwen is a hunter and third cousin related to Sam Winchester and Dean's mother's side of the family. When Sam re-enters Dean's life in "Exile on Main Street", he reveals that he has been back for a year and hunting with the Campbells, including Gwen.
She and the others assist the brothers in defeating a Djinn. Gwen is present at the compound in "Two and a Half Men" when the brothers arrive with a baby Shapeshifter, and is overpowered, along with the others, when the Alpha Shapeshifter arrives. When hunting the Alpha Vampire in "Family Matters", she is ordered to stay behind and flush out any stragglers with Dean. She and Dean fight well together, and she covers for Dean when he disobeys orders. However, she sides with Samuel Campbell at the end of the episode when she holds the Winchesters at gunpoint, and follows him even when it is revealed that he has been working for Crowley.
She is next seen in "...And Then There Were None", hunting with Samuel. While investigating a series of murders, they encounter Bobby Singer, Rufus Turner, Sam and Dean. Gwen tells Dean that she did not know that Samuel had betrayed them to Crowley. The creature responsible for the deaths—dubbed the Khan Worm—infects Dean, who kills Gwen.