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Arsenic and Old Lace is a 1944 American black comedy film directed by Frank Capra and starring Cary Grant. It was based on Joseph Kesselring's 1941 play, Arsenic and Old Lace. The script adaptation was written by Julius J. Epstein and Philip G. Epstein. The contract with the play’s producers stipulated that the film would not be released until the Broadway run ended. The original planned release date was September 30, 1942. The play was a tremendous hit, running for three and a half years, so the film was not released until 1944.

The lead role of Mortimer Brewster was originally intended for Bob Hope, but he could not be released from his contract with Paramount Pictures. Capra had also approached Jack Benny and Richard Travis before learning that Grant would accept the role. On the Broadway stage, Boris Karloff played Jonathan Brewster, who is said to "look like Boris Karloff". According to TCM, Karloff, who gave permission for the use of his name in the film, remained in the play to appease the producers, who were afraid of what stripping the play of all its primary cast would do to ticket sales. Raymond Massey took Karloff’s place on screen. The film's supporting cast also features Priscilla Lane, Jack Carson, Edward Everett Horton, and Peter Lorre.

Josephine Hull and Jean Adair portray the Brewster sisters, Abby and Martha, respectively. Hull and Adair, as well as John Alexander (who played Teddy Brewster), were reprising their roles from the 1941 stage production. Hull and Adair both received an eight-week leave of absence from the stage production, which was still running, but Karloff did not, as he was an investor in the stage production and its main draw. The entire film was shot within those eight weeks. The film cost just over $1.2 million of a $2 million budget to produce.

Plot[]

The Brewster family of Brooklyn, New York, is descended from Mayflower settlers. Several illustrious forebears' portraits line the walls of the ancestral home.

Mortimer Brewster, a writer who has repeatedly denounced marriage as "an old-fashioned superstition", falls in love with Elaine Harper, the minister's daughter who grew up next door to him. On Halloween day, Mortimer and Elaine get married. Elaine goes to her father's house to tell her father and pack for the honeymoon and Mortimer returns to Abby and Martha, the aunts who raised him in the old family home. Mortimer's brother, Teddy, who believes he is Theodore Roosevelt, resides with them. Each time Teddy goes upstairs, he yells "Charge!" and takes the stairs at a run, imitating Roosevelt's famous charge up San Juan Hill.

Searching for the notes for his next book, Mortimer finds a corpse hidden in the window seat. He assumes in horror that Teddy's delusions have led him to murder. Abby and Martha cheerfully explain that they are responsible, that as serial murderers, they minister to lonely old bachelors by ending their "suffering". They post a "Room for Rent" sign to attract a victim, then serve a glass of elderberry wine spiked with arsenic, strychnine, and "just a pinch of cyanide" while getting acquainted. The bodies are buried in the basement by Teddy, who believes they are yellow fever victims who perished in the building of the Panama Canal.

While Mortimer digests this information, his brother Jonathan arrives with his alcoholic accomplice, plastic surgeon Dr. Herman Einstein. Jonathan is also a serial murderer trying to escape from the police and dispose of his latest victim, Mr. Spinalzo. Jonathan's face, altered by Einstein while drunk, resembles Boris Karloff's Frankenstein monster makeup. Jonathan learns his aunts' secret and proposes to bury his victim in the cellar. Abby and Martha object vehemently because their victims were "nice" gentlemen while Jonathan's victim is a stranger and a "foreigner". Jonathan also declares his intention to kill Mortimer.

Elaine is impatient to leave on their honeymoon but is concerned about Mortimer's increasingly odd behavior as he frantically attempts to control the situation. He tries unsuccessfully to alert the bumbling police to Jonathan's presence. To draw attention away from his aunts and deprive them of their willing but uncomprehending accomplice, Mortimer tries to file paperwork to have Teddy legally committed to a mental asylum. Worrying that the genetic predisposition for mental illness resides within him ("Insanity runs in my family; it practically gallops"), Mortimer explains to Elaine that he can't remain married to her.

Eventually Jonathan is arrested, Einstein flees after having signed Teddy's commitment papers, Teddy is safely consigned to an institution, and his aunts insist upon joining him. Upon hearing that Mortimer signed the commitment papers as next of kin, Abby and Martha are concerned they may be null and void; they inform Mortimer that he is not a Brewster after all: his mother was the family cook and his father had been a chef on a steamship. Relieved, he lustily kisses Elaine and whisks her off to their honeymoon while yelling, "Charge!".

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